Sauer Group
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Systems Biology of Metabolism
The mission of our systems biology research is to identify and quantify the key regulation mechanisms that control cellular metabolism in microbes.
The speciality of our interdisciplinary team of biologists, engineers, and computer scientists are high-throughput experimental technologies for quantitative metabolomics, 13C-based intracellular flux analysis, and dynamic GFP analysis in mini-scale cultivations. Different types of mathematical models are then used to quantitatively relate metabolomics, expression and proteomics data to the functional network output in terms of fluxes. Read more
Contact
Inst. f. Molekulare Systembiologie
Otto-Stern-Weg 3
8093
Zürich
Switzerland
Group news
Kian Bigovic Villi starts his PhD at IMSB
Kian started his PhD in early January 2025, supervised by Julian Trouillon and Uwe Sauer. He will be working on the effects of post-translational modifications on transcription factor activity. Welcome back Kian, and all the best!
Master/Semester computational project: Predicting transcription factors input signals using network analysis
In this project, we aim at inferring input signals affecting transcription factors activity using computational analysis of regulatory and metabolic networks.
Sauer Zamboni group achieves LEAF sustainability certification!
The group was one of 19 labs across ETH Zurich to be certified in the LEAF pilot project.
We welcome Jonas Runde as a new PhD student in the lab!
Jonas started his PhD in the group in December, working on protein phosphorylation and post-translational modifications in E. coli. Welcome back Jonas, and viel Erfolg!