Dr. Anna Weiser
Metabolic Flux Analysis
Anna started as a postdoctoral researcher in the Zamboni lab in May 2023. She is particularly interested in the analysis of metabolic pathways, especially those relevant to mitochondrial functionality. Her current project focuses on the study of metabolic flux analysis for clinical research and diagnostics related to leukemia.
In her PhD research, she investigated the mitochondrial calcium uniporter (MCU) and its regulatory function for mitochondrial redox state. She showed that the MCU promotes a reduced mitochondrial redox state, which, among other findings, is beneficial for energy metabolism in human skeletal muscle.
Education
- PhD in Molecular Nutritional Medicine at TU Munich (TUM) and Nestlé Research (NR) Lausanne, supervised by Professor Hannelore Daniel (TUM) and Dr. Umberto De Marchi (NR).
- Master in Nutrition & Biomedicine at TUM, thesis in the lab of Professor Hannelore Daniel.
- Bachelor in Nutritional Sciences at TUM.
- Bachelor in Economics at the University of Mannheim.
Selected Publications
- external page Mitochondrial Calcium Uptake Declines during Aging and is Directly Activated by Oleuropein to Boost Energy Metabolism and Skeletal Muscle
- external page The mitochondrial calcium uniporter (MCU) activates mitochondrial respiration and enhances mobility by regulating mitochondrial redox state
- external page Acylcarnitine Profiles in Plasma and Tissues of Hyperglycemic NZO Mice Correlate with Metabolite Changes of Human Diabetes