2017

A summary of the second half of the year. Read more

We just received the exciting news that Paola will get the 2018 Friedrich-Miescher-Award from the Molecular and Cellular Biosciences section of Life Sciences Switzerland. Congratulations to her!

A position is open for a postdoctoral research assistant in the Computational Biology Group at the Institute of Molecular Systems Biology at ETH Zürich. The available position is offered in Claassen group that focuses on concepts from statistics, machine learning and mathematical optimization to describe biological systems from single cell data. We are looking for you as of now, or upon agreement, as a

Identification of biomarkers and therapeutic targets in inflammatory disease immunotherapy by high-dimensional single cell analysis and cluster proteomics

The project is a collaboration with the group of Tanya Petrova (University Lausanne) and Pia Ostergaard (St. George’s Hospital and University of London, UK). We aim at advancing our understanding of fundamental biological mechanisms driving formation and function of lymphatic vasculature in normal and pathological conditions.

Seven projects co-submitted by IMSB members were approved in the 1st joint PHRT-SPHN call. >4 Mio CHF will flow to our Institute to develop, apply, and promote innovative technologies and platforms for personalized health.

The Christen and Wollscheid labs hosted the "Zukunftstag @ IMSB this year

We are delighted to announce that the PSSS consortium was selected by the SPHN and PHRT panels for funding (>5 Mio CHF). The Swiss-wide consortium is headed by Prof. Adrian Egli (Uni Basel) and Prof Karsten Borgwardt (ETH Zürich). The Zamboni lab is responsible for the molecular profiling of >8000 plasma samples.

We are glad to announce that our SFA-PHRT technology transfer project proposal "Strategies and standards for high-throughput, long-term, non-targeted metabolome analysis of human biofluids" has been funded!

The joint proposal that combines synthetic Biology (Prof De Mey, Ghent University) and systems biology (Zamboni lab) has been just approved by the FWO/SNF. Looking forward to joining forces!

Mass Spectrometric Analysis of Hepatitis B Virus X Proteoforms and Interactomes.

Congrats to almost all of us: the protocol paper in which we practically describe the method of coupling limited proteolysis to mass spectrometry is now out in Nature Protocols! This will be an important starting point for external labs to try out this exciting and powerful method.

A warm welcome to Patrick Stalder and Monika Pepelnjak who have started their PhD-project and fast track Master/PhD-project, respectively, in our lab.

The project lies at the intersection of genetics, psychophysics of smell, and data democracy. Students will have the opportunity to combine wet lab work, study design, and computational analysis. Students should be able to write simple scripts in R, Matlab, or Python or have the willingness to acquire and develop these skills. 

Congratulations to Yuehan, Valentina and Paola as their review on quantitative proteomics of model organisms is now published in Current Opinion in Systems Biology. 

'Systems proteomics approaches to study bacterial pathogens: application to Mycobacterium tuberculosis' was published in an issue of Current Opinion in Microbiology focused on Bacterial Systems Biology.

Although they did not yet move their lab physically, the Picotti group has just changed affiliation by joining the Institute of Molecular Systems Biology of ETH Zurich, where Paola obtained a tenured position. 

We are excited to welcome Cathy Marulli, Martin Steiner and Philipp Schächle, who start their Bachelor, Semester and Master projects in our group.

Our joint paper with the Vorholt Lab, ETHZ was published in Current Biology.

In this project, we aim at inferring functional protein-metabolite interactions in the bacterium Escherichia coli from dynamic metabolomics data.