Sauer-Picotti collaboration results in publication in Sci Transl Med
Congrats to Ilaria and Paola as their collaboration with the Sauer group and groups in Basel and Paris led to a paper in Science Translational Medicine: High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds.
by
Paul Boersema
Specifically, Ilaria helped out to perform LiP-MS experiments to probe protein conformational changes in M. tuberculosis after incubation with the GSK2623870A compound. Several conformational changes were found in proteins involved in fatty acid metabolism.
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