2018

A summary of the second half of 2018. Read more

Whether dormant bacteria begin to reproduce is no accident. Rather, they are simply waiting for a clear signal from a single protein in the cell interior. The Sauer lab have now deciphered the molecular mechanisms behind this.

The article "The in silico human surfaceome" has recently been published in PNAS and now has been recommended by the F1000 member Alejandro Schaffer to be of special significance in its field.

Congrats to the Robinson lab and Maik Müller for getting their paper out about the molecular mechanims of action of thanatin, natural occuring antimicrobial peptide that kills Gram-negative bacteria.

Together with the rest of IMSB we moved our lab to new a building, which meant 2-fold increase in office and lab space. We now got space to separate office and lab work, so we now can enjoy a coffe while doing bioinformatic analysis without atleast fearing that the coffe is contaminated. The move also meant we now got dedicated space for clinical proteomic work. You can now find us in the HPM2 building on the D floor for the clinical facilities and F floor for the research facilities. 

Our work on the identification of small molecule modulators of diguanylate cyclase by FRET-based high-throughput-screening was published in ChemBioChem.  

We welcome back Alex in our lab. She has been a Masters' student and now she will stay with as a research intern. Good luck, Alex!

Together with the rest of IMSB we moved our lab to a new building. For us it meant a physical move of one floor down and a few meters back, but it gave use the opportunity to put together a nice, big, open-space lab and equip it with all new instruments and items. You can find us now in HPM2, D24. Our mass specs joined the mass specs of the other IMSB groups in a massive underground lab. Watch some pictures of the progress

Congrats to the Wollscheid lab to get their paper on predicting cell surface proteins published in PNAS!

Congratulation to Monika! She was awarded the ETH Medal for Outstanding Master Theses for the work she did in our lab as a Masters' student. Way to go!  

Surfaceome nanoscale organisation and its extracellular interaction network determines cellular identity and fate. This review discusses different surfaceome models and which factors incluence their organisation.

Big congratulation to Ilaria for winning the Early Career Researcher competion 'highlight of the year'!   

The Wollscheid lab has been successful in publishing some long-standing studies: 1. The HATRIC paper 2. Proteomic profiling of poxvirus assembly 3. An antibiotic interactions study in pseudomonas aeruginosa

Jonas Albinus (from Denmark) and Sebastian Steiner (from Switzerland) just started as PhD students in the Wollscheid lab. They will be working on clinical proteomics and we wish them a good start!

Our tutorial article describing everything you need to know to get started with DIA is now (finally!) published.

The video lectures from the our week-long course focused exclusively on DIA/SWATH are now online.

The Christenlab received the first bench-top iSeq DNA sequencing instrument in Switzerland. The iSeq combines CMOS with on-chip sequencing by synthesis technology.

Our TnSeq study in collaboration with Xavier DeBolle was published in Infect. Immun.

A big welcome to Christian Dörig who is starting in our group as a PhD student. All the best for your project!

We welcome Marie-Therese Mackmull to our lab as a post-doctoral fellow!