Several new publications by the Wollscheid lab

The Wollscheid lab has been successful in publishing some long-standing studies: 1. The HATRIC paper 2. Proteomic profiling of poxvirus assembly 3. An antibiotic interactions study in pseudomonas aeruginosa

by Damaris Bausch-Fluck

external pageHATRIC-based identification of receptors for orphan ligands. / Nature Communications

HATRIC is an evolved molecule from TriCEPS and provide the possibility to identify ligand-receptor pairs in physiological conditions with limited number of cells.

external pageProteotype profiling unmasks a viral signalling network essential for poxvirus assembly and transcriptional competence/ Nature Microbiology

Phosphoproteomic profiling of the signalling network of the viral signaling mediators and kinase-phosphatase pair F11 and H10. This work elucidates a proteotype-phenotype-genotype relationship.

external pageA Peptidomimetic Antibiotic Interacts with the Periplasmic Domain of LptD from Pseudomonas aeruginosa. / Chemical Biology

Characterization of the interaction site of the antibiotics Murepavadin with LptD from P. aeruginosa, by cross-linking it to a photolabeling probe.

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