De novo Classification of Mouse B Cell Types using Surfaceome Proteotype Maps
Interested in a new way of classifying B Cell types then have a look at a recently paper from our lab which is now on BioRxiv.
Abstract
System-wide quantification of the cell surface proteotype and identification of extracellular glycosylation sites is challenging when sample is limiting. We miniaturized and automated the previously described Cell Surface Capture technology increasing sensitivity, reproducibility, and throughput. We used this technology, which we call autoCSC, to create population-specific surfaceome maps of developing mouse B cells and used targeted flow cytometry to uncover developmental cell subpopulations.
