Our paper on alpha-synuclein toxicity out in Cell Systems!

Former graduate student Martin Soste studied mechanisms of genes that modulate alpha-Syn toxicity. He used the lab's "sentinel assay" to monitor the activation state of ~200 pathways in yeast and found that blocking the biosynthesis of diacylglycerol, a precursor of lipid droplets, rescued cells from toxicity. Read the paper here: https://doi.org/10.1016/j.cels.2019.07.010